General enquiries

  • What is deprexis® ?

    deprexis® is an individualized and convenient online treatment for depression. Its effectiveness has been shown in more than ten randomised controlled trials. deprexis® is a certified medical device, which aims to help patients change certain thinking habits and behavioral patterns that contribute to depression. Thereby, deprexis®empowers patients to overcome depression and supports other depression treatments that patients may receive. However, the use of deprexis® does not replace a doctor or psychotherapist.

  • How does deprexis® work?

    deprexis® is based primarily on the methods of cognitive behavioral therapy (CBT). It contains 10 subject areas - such as cognitive aspects (E.G., coping with persistent negative thoughts), behavioural aspects (E.G., scheduling activities that may counteract depression), social skills or effective problem-solving techniques, among others. The online therapy support programme engages patients in individual dialogues, teaches them techniques to promote well-being, encourages self-monitoring of symptoms, and accompanies them through e-mail and/or SMS contacts (SMS only available in some countries). The overall aim of the programme elements is to teach patients useful skills they can apply in everyday life to overcome depression.

  • What technical skills do I need to use deprexis®?

     No special technical skills are required to use the online therapy support program.

  • Can I combine deprexis® with medication ?

    Yes, deprexis® can be combined with medications (such as antidepressants). You should not discontinue taking your doctor's or psychotherapist's prescribed medications independently.

  • Can I restart the online therapy program or pass it on to third parties ?

    No, deprexis® is an interactive, personalized, ongoing online therapy program. The online therapy programme learns about you, suggests exercises tailored to your needs and responds individually to your responses. That is why deprexis®cannot and should not be passed on to third parties.

  • Can I use deprexis on my smartphone ?

    Yes, you can use deprexis® on many internet-enabled devices such as notebooks, PCs, smartphones or tablets. You can also switch between different devices at any time. This way you can use deprexis® via your smartphone or tablet while you are on the move, and for example carry out the exercises or listen to audios.

    The following internet browsers are supported:

    Notebook or PC:

    • Mozilla Firefox (current version)
    • Google Chrome (current version)
    • Edge (current version)
    • Windows Internet Explorer 11 (current version)
    • Safari (current version)

    Smartphone or Tablet:

    • Google Chrome (current version using Android)
    • Mobile Safari (current version - iPhone, iPad, iPod Touch)
  • Can I use the therapy program again after the 90 days, is there a "continuation" ?

    Unfortunately, an extension of a deprexis® access is not possible. If you want to restart using deprexis® you can buy a new voucher code here.

  • Have you got any good reading recommendations for self-help literature?

    deprexis is more than a self-help book, as it responds to you personally. Of course, there are also very good self-help books that you can read to help you cope with depression. Here's a list of current titles:

    Achor S. The happiness Advantage: The seven principles of positive psychology that fuel success and perfomance at work. New York: Crown Business; 2010.

    Addis ME, Martell CR. Overcoming depression one step at a time. The new behavioral activation approach to getting your life back. Oakland: New Harbinger Publications; 2004.

    Burns DD. Feeling good: The new mood therapy revised and updated. New York: Avon Books; 1999.

    Davis M, Eshelman ER, McKay D. The relaxation & stress reduction workbook. 6th ed. Sydney: New Harbinger Publications; 2008.

    Fast JA, Preston JD. Get it done when you're depressed : 50 strategies for keeping your life on track. New York: Penguin Group (USA) Inc.; 2008.

    Greenberger D, Padesky CA. Mind over mood: A cognitive therapy treatment for clients: Cognitive treatment therapy manual for clients. New York: Guilford Press; 1995.

    Hayes SC, Smith S. Get out of your mind and into your life. The new acceptance and commitment therapy. Oakland: New Harbinger Publications; 2005.

    Jeffers S. Feel the fear ... and do it anyway. New Ed. London: Arrow; 2011.

    Kabat-Zinn J. Guided mindulfness mediation [Audiobook]. Louisville: Sounds True; 2005.

    Kabat-Zinn J. Wherever you go, there you are: Mindfulness meditation in everyday life. New York: Hyperion Books; 2005.

    Lyubomirsky S. The how of happiness: A new approach to getting the life you want. London: Penguin Books; 2008.

    Morris J. The dream workbook: Discover the knowledge and power hidden in your dreams. London: Little, Brown and Company; 2002.

    Pennebaker JW. Opening up. The healing power of expressing emotions. New York: The Guilford Press; 1997.

    Quinn P. Freedom from fear: Taking back control of your life and dissolving depression. Lake George: Peyton Quinn Publishing; 2004.

    Seligman MEP. Authentic happiness. Using the new positive psychology to realize your potential for lasting fulfilment. London: Nicholas Brealey Publishing; 2003.

    Seligman MEP. Learned optimism: How to change your mind and your life. New York: Vintage Books; 2006.

    Williams C. Overcoming depression and low mood. A five areas approach. 3rd ed. London: Hodder Arnold; 2012.

    Williams M, Teasdale J, Segal Z, et al. The mindful way through depression. Freeing yourself from chronic unhappiness. 1st ed. New York: The Guilford Press; 2007.

    Young JE, Klosko JS, Beck AT. Reinventing your life: The breakthrough program to end negative behavior ... and feel great again. New York: Penguin Group (USA) Inc.; 1994.

  • How often should I use deprexis® and for how long ?

    You can always use deprexis® at your own pace and for as long as it suits you. deprexis® is meant to support you - you can decide how often and for how long you want to use it. Experience shows that it's worthwhile to use the program 1-2 times a week for at least 30 minutes. You should also take time to incorporate the techniques and exercises into your daily routine. Of course, you can also use deprexis® more frequently if you want to or need to. Please also consult your doctor or therapist on this topic.

  • How often should I use deprexis® ?

    You can always use deprexis® at your own pace and for as long as it suits you. deprexis® is meant to support you - you can decide how often and for how long you want to use it. Experience shows that it's worthwhile to use the program 1-2 times a week for at least 30 minutes. You should also take time to incorporate the techniques and exercises into your daily routine. Of course, you can also use deprexis®more frequently if you want to or need to. Please also consult your doctor or therapist on this topic.

  • Is deprexis® the right therapy for me?

    The mode of action of deprexis® can be compared to psychotherapy, in particular cognitive behavioural therapy (CBT). That is, by learning CBT skills, patients are empowered to recognize and alter thinking habits and behavioral patterns that create and maintain depression. deprexis® engages patients in interactive dialogues in order to explore their concerns and offer individualized content that is personally relevant. deprexis(r) guides patients through custom-tailored exercises that allow them to experience relaxation or mindfulness, acquire new skills for coping with persistant negative thoughts, or develop action plans for daily life. Daily e-mail suggestions support the treatment and help transfer skills into everyday life. Some patients may find that dealing with troubling issues is difficult or upsetting. If that is the case, patients are encouraged to take a break, stop using the programe, and talk to their doctor or psychotherapist.

  • What are the risks or side effects ?

    "It is possible that not every patient will benefit from using this program, which may trigger feelings of disappointment. It is possible that some patients may find it difficult to deal with upsetting subjects. If working with the program becomes too upsetting, patients should take a break, stop using the program and talk to their physician or psychotherapist about this. Not every exercise is equally suitable for every patient. If an exercise proves difficult for patients, makes them feel uncomfortable, or affects them negatively, they should not continue with that exercise. If necessary, they should speak to their physician/psychotherapist. Should patients experience any side effects while using deprexis, they should inform their physician or psychotherapist immediately or send an email to"

  • Where does the deprexis content come from?

    deprexis® was developed by a team of psychologists, physicians, software engineers and communication experts. All of the content is based on findings from research on depression and on practical real-life experience from working with patients. Here's a list of some of the scientific literature that we used in developing the program:

    Addis ME, Truax P, Jacobsen NS. Why do people think they are depressed?: The Reasons For Depression Questionnaire. Psychotherapy: Theory, Research, Practice, Training 1995;32(3):476-483.

    Baer RA. Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology: Science and Practice 2003;10(2):125-143.

    Beck JS. Cognitive therapy: Basics and beyond. New York: The Guilford Press; 1995.

    Beck AT, Rush AJ, Shaw BF, et al. Cognitive therapy of depression. New York: Guilford Press; 1979.

    Bono G, McCullough ME. Positive responses to benefit and harm: Bringing forgiveness and gratitude into cognitive psychotherapy. Journal of Cognitive Psychotherapy 2006;20(2):147-158.

    Brandt H, Grose S. Weniger Stress durch Meditative Entspannung, Audio-CD mit Begleitheft, Entspannungsübungen zum Wohlfühlen mit Anleitungen zur Meditation der Achtsamkeit. (Audiobuch). Hannover: Henrik Brandt Verlag; 2005.

    Davis M, Robbins Eshelman E, McKay M. The relaxation and stress reduction workbook, 5th ed. Oakland, CA: New Harbinger; 2000.

    Deci EL, Ryan RM. The "what" and "why" of goal pursuits: Human needs and the self-determination of behavior. Psychological Inquiry 2010;11(4):227-268.

    Dimidjian S, Hollon SD, Dobson KS, et al. Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. Journal of Consulting and Clinical Psychology 2006;74(4):658-670.

    Dunn AL, Trivedi MH, Kampert JB, et al. Exercise treatment for depression: Efficacy and dose response. American Journal of Preventive Medicine 2005;28(1):1-8.

    Epstein S. Cognitive-experiential self-theory. In: Barone DF, Hersen M, Van Hasselt VB, (Eds.) Advanced personality. New York, NY: Plenum Press; 1998. p. 211-238.

    Esterling BA, L'Abate L, Murray EJ, et al. Empirical foundations for writing in prevention and psychotherapy: Mental and physical health outcomes. Clinical Psychology Review 1999;19(1):79-96.

    Gable SL, Reis HT, Impett EA, et al. What do you do when things go right? The intrapersonal and interpersonal benefits of sharing positive events. Journal of Personality and Social Psychology 2004;87(2):228-245.

    Gortner ET, Gollan JK, Dobson KS, et al. Cognitive-behavioral treatment for depression: Relapse prevention. Journal of Consulting and Clinical Psychology 1998;66(2):377-384.

    Grawe K. Neuropsychotherapie. Göttingen: Hogrefe; 2004.

    Hayes SC, Strosahl KD, Wilson KG. Akzeptanz und Commitment Therapie: Ein erlebnisorientierter Ansatz zur Verhaltensänderung. München: CIP; 2004.

    Hayes SC, Smith S. Get out of your mind and into your life: The new acceptance and commitment therapy. Oakland, CA: New Harbinger; 2005.

    Hill CE. Dreams and therapy. Psychotherapy Research 1996;6:1-15.

    Hill CE, Crook-Lyon RE, Hess SA, et al. Prediction of session process and outcome in the Hill dream model: Contributions of client characteristics and the process of the three stages. Dreaming 2006;16:159-185.

    Jacobson NS, Dobson KS, Truax PA, et al. A component analysis of cognitive-behavioral treatment for depression. Journal of Consulting and Clinical Psychology 1996;64(2):295-304.

    Kabat-Zinn J. Mindfulness-based interventions in context: Past, present and future. Clinical Psychology: Science and Practice 2003;10(2):144-156.

    Kabat-Zinn J, Kesper-Grossman U. Stressbewältigung durch die Praxis der Achtsamkeit. Freiamt im Schwarzwald: Arbor Verlag; 1999.

    Keyes CLM, Haidt J. Flourishing: Positive psychology and the life well-lived. Washington, DC: American Psychological Association; 2003.

    Klerman G, Weissman M, Rounseville B, et al. Interpersonal psychotherapy of depression. New York: Basic Books; 1984.

    Martell CR, Addis ME, Jacobson NS. Depression in context: Strategies for guided action. New York: Norton; 2001.

    McQuaid JR, Carmona PE. Peaceful mind: Using mindfulness and cognitive behavioral psychology to overcome depression. Oakland, CA: New Harbinger; 2004.

    Meyer B, Garcia-Roberts L. Congruence between reasons for depression and motivations for specific interventions. Psychology and Psychotherapy: Theory, Research and Practice 2007;80(4):525-542.

    Morris J. The dream workbook: Discover the knowledge and power hidden in your dreams. New York: Fawcett Crest; 1985.

    Mynors-Wallis LM. Problem-solving treatment for anxiety and depression: A practical guide. Oxford, UK: Oxford University Press; 2005.

    Mynors-Wallis LM, Gath DH, Lloyd-Thomas AR, et al. Randomised controlled trial comparing problem-solving treatment with amitriptyline and placebo for major depression in primary care. British Medical Journal 1995;310(6977):441-445.

    Mynor-Wallis LM, Gath D, Day A, et al. Randomised controlled trial of problem-solving treatment, antidepressant medication and combined treatment for major depression in primary care. British Medical Journal 2000;320(7226):26-30.

    Nezu A. Efficacy of a social problem-solving therapy approach for unipolar depression. Journal of Consulting and Clinical Psychology 1986;54(2):196-202.

    Pennebaker JW. Writing to heal. Oakland, CA: New Harbinger; 2004.

    Pennebaker JW. Opening up: The healing power of expressing emotions. New York, NY: Guilford Press; 1997.

    Reis HT, Sheldon KM, Gable SL, et al. Daily well-being: The role of autonomy, competence, and relatedness. Personality and Social Psychology Bulletin 2000;26(4):419-435.

    Richardson CR, Avripas SA, Neal DL, et al. Increasing lifestyle physical activity in patients with depression or other serious mental illness. Journal of Psychiatric Practice 2005;11(6):379-388.

    Ryan RM, Deci EL. The darker and brighter sides of human existence: Basic psychological needs as a unifying concept. Psychological Inquiry 2000;11(4):319-338.

    Segal ZV, Williams S, Teasdale J. Mindfulness-based cognitive therapy for depression: A new approach to preventing relapse. New York: Guilford; 2002.

    Seligman MEP. Der Glücks-Faktor: Warum Optimisten länger leben. Bergisch-Gladbach: Verlagsgruppe Lübbe; 2005.

    Seligman MEP, Csikszentmihalyi M. Positive psychology: An introduction. American Psychologist 2000;55(1):5-14.

    Seligman MEP, Rashid T, Parks AC. Positive psychotherapy. American Psychologist 2006;61(8):774-788.

    Seligman MEP, Steen TA, Park N, et al. Positive psychology progress: Empirical validation of interventions. American Psychologist 2005;60(5):410-421.

    Sheldon KM, Williams G, Joiner T. Self-determination theory in the clinic: Motivating physical and mental health. New Haven, CT: Yale University Press; 2003.

    Sheldon KM, Niemiec CP. It's not just the amount that counts: Balanced need satisfaction also affects well-being. Journal of Personality and Social Psychology 2006;91(2):331-341.

    Sheldon KM, Elliot AJ, Kim Y, et al. What is satisfying about satisfying events? Testing 10 candidate psychological needs. Journal of Personality and Social Psychology 2001;80(2):325-339.

    Snyder CR, Lopez SJ. Handbook of positive psychology. London: Oxford University Press; 2002.

    Stetter F. Entspannungsverfahren. Wirksame Komponenten psychotherapeutischer und psychiatrischer Behandlung. Psychotherapeut 2004;49(4):281-291.

    Suinn RM. Anxiety management training: A behavior therapy. New York, NY: Plenum Press; 1990.

    Trösken AK, Grawe K. Inkongruenzerleben aufgrund brachliegender und fehlender Ressourcen: Die Rolle von Ressourcenpotentialen und Ressourcenrealisierung für die psychologische Therapie. Verhaltenstherapie und Psychosoziale Praxis 2004;36:51-62.

    Williams M, Teasdale J, Segal Z, et al. The mindful way through depression: Freeing yourself from chronic unhappiness. New York, NY: Guilford Press; 2007.

Security & Anonymity

  • What about data protection - is my data secure ?

    We take the protection of your personal data, e.g. your email address and other details, very seriously, and only ask for these to facilitate your use of deprexis. Your personally identifiable data will not be given to third parties nor be used for marketing purposes. Your data is saved according to data protection regulations. More information about data protection can be found in the deprexis®terms and conditions.

    Data transmission takes place over a secure HTTPS internet connection; your details are encrypted by SSL.

    Deprexis® is not installed on the end devices as a program, but you can only access the program online, no data is stored on the end device. 


  • Can I test deprexis® before I buy it ?

    Yes, there is a test version for deprexis, called "deprexis® go!". It can be found on our homepage or access it directly here: deprexis® go!. "deprexis® go!" is not the same as deprexis® but you can get a good impression of how the programme works, what it looks and feels like, and whether it may suit your needs.

  • How do I get deprexis® ?

    deprexis® can be purchased directly on the website You will receive a personal access code by e-mail immediately after the payment.

  • How long is my deprexis®access valid for ?

    Your deprexis® access is valid for 90 days from the day of registration. For this period, you will have access to helpful information about coping with depression. At any time, you can keep track of which access code you have registered with for your current use period, and how long your access is still valid for.

  • I would like to purchase the access code for deprexis®, but I do not live in Germany. Can I still order via the shop?

    The access codes for deprexis® can only be sold via the online shop and only to persons who order from one of the countries listed below. If you are not resident of one of the following countries and you are interested in deprexis®, please contact GAIA AG directly (

    • Germany
    • Brazil 
  • Is it possible to quit the program at any time?

    Yes, you can stop using the program at any time during the 3 month usage period.

  • Is there a right of return ?

    No, unfortunately there is no right of return after purchasing deprexis®.

  • My doctor/psychotherapist prescribed deprexis® for me, do I still have to bear the costs?

    Yes, deprexis® is currently a self-payer benefit. However, you can try to get the costs back from your health insurance, but the health companies are currently not obliged to do so. After purchasing deprexis®, an invoice will be sent to your specified e-mail.

  • Which payment options are there ?

    To start the online therapy program immediately, you can pay for Deprexis® by Credit and Debit card (Visa, MasterCard).

    You can paid the totality of the amount during the purchase or split the payment in three installments.

Using Deprexis

  • How do I register with deprexis® ?

    To use deprexis® , you must register with the access code at, then follow the instructions of the program. The registration can be anonymous, you only need an e-mail address and an individual password. If you want to register anonymously, use an email address that does not contain personal data (name, year of birth, etc.). After registering, you can use deprexis® around the clock - flexibly and independently.

  • I am a therapist and am sceptical about deprexis®. How can I use deprexis® for my patients benefit?

    deprexis® aims to enhance the availability of psychotherapeutic care and support face-to-face psychotherapy. In fact, a recent study has shown that when deprexis®is added to psychotherapy, the effect size is significantly higher compared to psychotherapy alone. Using deprexis®can free up time that would otherwise be required for, E.G., psychoeducation. This may allow therapists to use their personal sessions in a more focused manner in order to work on clients’ individual issues.

  • I cannot log in. What am I doing wrong?

    If you want to access deprexis®for the first time,please click “register” on the deprexis®homepage and insert your voucher code. After you have registered you can always log in via the “login” button with thelogin credentialsyou generated during the registration process.

  • I cannot sign in, even though I am doing everything exactly the way I usually do.

    If you cannot log in, the easiest way to access your account is to click “New password” and to generate a new password. If you have forgotten your e-mail address you can also use your voucher code to find your account.

  • The answer possibilities in the chats do not always fit my situation. What should I do?

    It can of course happen that you won't always find an answer that fits exactly for you. This is normal and you do not need to worry about it. In this case, simply spontaneously choose the answer that seems the best to you. deprexis®will then attempt to act on this and to direct the conversation in the right direction. 

    Do not worry: deprexis®is built in a way that means you won't miss out on any information that could be personally helpful to you. 

  • Where can I change my details (E.G. name and email address)?

    If you want to choose a new name or change your email address or mobile phone number, you can do that here: Settings

    You can choose a new password here:


    You can edit your gender and age details if you need to here:


  • Where can I download the audio files ?

    Unfortunately, it is not possible to download the audio files locally to your electronic device. However, you can listen to your audios whenever and as often as you want in “your area” and under “Your exercises”.

  • Where can I find deprexis ?

    deprexis®is a browser-based programme, so you can access it from almost anywhere, any time. You can find deprexis®on

  • Why can't I go back and choose another answer in chats ?

    The idea behind deprexis® is to conduct a dialogue or "chat" that simulates a real conversation. In a conversation, we can't just press "rewind". We want to make the dialogue feel as "real" as possible for you. So, deprexis® does not consist of a series of standard pages or websites one after another - which is the case for most web programs, and which allows you to use the "back" button - but it responds to your answers dynamically, according to what you choose. So going "back" in your browser just doesn't make sense with deprexis®.

    But if you want to, you can also repeat sessions: as soon as you have completed all of the deprexis® chats, they become available to you again. You can then repeat it, as often as you wish. That way you can also review any thoughts and suggestions you might want to look at again.

  • Why do I need to confirm my email address and mobile number?

    If you confirm your email address and mobile number, you can profit more from deprexis. For example we can then help you if you lose your password, and we can also send you emails and text messages with helpful suggestions and tips for dealing with depression. Apart from this, confirming your email address and mobile number helps to ensure the security of your data.

    In case you haven't done it yet - please confirm your email address and mobile phone number here:


  • Why do you need my mobile number ?

    If you enter your number you will receive a daily SMS message from deprexis, which many users have found very helpful. You can enter this directly at registration or choose to do so in your deprexis®settings later when you log in.

    The SMS/text message service is free of charge in the country in which you complete your registration. For use outside of this country you are responsible for roaming and other equivalent charges.

    Naturally, you can choose to end or pause the sending of deprexis®SMS messages, for example to avoid roaming charges if you're travelling abroad. To do this, simply delete your mobile phone number in your deprexis®settings. If you want to receive SMS messages again later, enter your mobile phone number again and confirm this.  Your mobile number will be handled confidentially and will only be used to send you deprexis®text messages. It will not be given to third parties or used for marketing purposes. Storage is done in accordance with the required data protection regulations. Please not that deprexis®SMS are not available for every country and language.


  • Can I contact you in an emergency?

    In emergencies or when needed, contact your doctor or psychotherapist or telephone counseling. The telephone counseling can be reached around the clock under the telephone number 141, here you receive competent, confidential and anonymous assistance.

    Further help is also available under the known emergency numbers.

    Police: 190

    Medical Emergencies (SAMU): 192

  • How can I get my bill ?

    You can download your bill on the last step of the purchase. For the security of your personal data we do not send you your bill by e-mail.

    If you want to get your bill after the payment you can ask for it on our contact page, there is a special section.

  • I am a researcher and I would like to conduct a study on deprexis®. Can I do that and how should I proceed ?

    If you are interested in conducting a study on deprexis, please feel free to contact our research team by email: